Continuous prednisolone versus conventional prednisolone with VMCP-interferon-alpha2b as first-line chemotherapy in elderly patients with multiple myeloma
نویسندگان
چکیده
منابع مشابه
CLINICAL TRIALS AND OBSERVATIONS Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma
1Department of Medicine I, Wilhelminenspital Vienna, Vienna, Austria; 2Internal Hematooncological Clinic, Faculty Hospital Brno and Faculty of Medicine MU, Brno, Czech Republic; 3Clinic of Hematology, Faculty Hospital with Policlinic, Kosice, Slovakia; 4Clinical Division of Oncology, Medical University of Vienna, Vienna, Austria; 5Clinical Hospital “Rebro,” Zagreb, Croatia; 6Department of Inter...
متن کاملThalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma.
We compared thalidomide-dexamethasone (TD) with melphalan-prednisolone (MP) in 289 elderly patients with multiple myeloma (MM). Patients received either thalidomide 200 mg plus dexamethasone 40 mg, days 1 to 4 and 15 to 18 on even cycles and days 1 to 4 on odd cycles, during a 28-day cycle or to melphalan 0.25 mg/kg and prednisolone 2 mg/kg orally on days 1 to 4 during a 28- to 42-day cycle. Pa...
متن کاملPrognostic factors in multiple myeloma treated with prednisolone and sequential melphalan and ifosfamide: MIP combination chemotherapy.
Response rates and survival times were studied in 47 patients who had multiple myeloma and who were being treated with Prednisolone and sequential Melphalan and Ifosfamide (MIP therapy). The clinical response was determined by objective parameters such as the reduction of M-protein level, tumor volume and healing of bone destruction. Twenty-eight of the patients (59.6%) responded to the MIP the...
متن کاملCombination chemotherapy for multiple myeloma with melphalan, ifosfamide, prednisolone, nitrosourea and vincristine.
Melphalan, ifosfamide, prednisolone, nitrosourea [1-(4-amino-2-methyl-5-pyrimidyl)-3-(2-chloroethyl)-3-nitrosourea hydrochloride, ACNU or 1, 3-bis (2-chloroethyl)-1-nitrosourea, BCNU] and vincristine (MIP-NV) were given in combination to 48 patients with multiple myeloma. The response rate was 57% in previously untreated patients, and 39% in previously treated patients. The median survival time...
متن کامل974pprospective Study of Melphalan, Prednisolone and Lenalidomide in the Treatment of Elderly Patients with Newly Diagnosed Multiple Myeloma.
Methods: This is a prospective study of newly diagnosed multiple myeloma patients above 60 yrs and ineligible for peripheral blood stem cell transplant and attending medical oncology department at Regional Cancer Centre, Trivandrum, India.The recruitment period was from January 2012 to September 2013. The study was approved by Institute Ethics committee. Baseline physical examination, laborator...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2005
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.2005.05779.x